The effect of systemic levels of TNF-alpha and complement pathway activity on outcomes of VEGF inhibition in neovascular AMD.

Adnan H KhanCharles O PierceGabriella De SalvoHelen GriffithsMarie NelsonAngela Jane CreeGeeta MenonAndrew John Lotery

Published in: Eye (London, England) (2021)

Lower serum TNF-α levels were associated with an increase in visual acuity after anti-VEGF therapy. This suggests that targeting pro-inflammatory cytokines may augment treatment for neovascular AMD.

Keyphrases

age related macular degeneration
vascular endothelial growth factor
rheumatoid arthritis
endothelial cells
cancer therapy
drug delivery
type diabetes
cell therapy
replacement therapy
skeletal muscle
mesenchymal stem cells
weight loss
chemotherapy induced