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Managing suspected myasthenia gravis and myositis induced by pembrolizumab in a Jehovah's Witness sarcoma patient.

Alexander HutchinsonDanielle EskensAbigail ChanAnika BhargavaRyan Bycroft
Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2024)
While neurologic adverse events typically present 6 weeks after initiation of ICIs, MG has been reported occurring as early as 4 weeks after initiation. This rare and serious adverse event requires prompt treatment, and clinicians need to be aware of the alternative treatment options in this unique patient population. Early conversations regarding blood products and factions must be had to develop a treatment plan in accordance with the patient's personal decisions.
Keyphrases
  • myasthenia gravis
  • case report
  • emergency department
  • rheumatoid arthritis
  • systemic sclerosis
  • replacement therapy
  • epidermal growth factor receptor
  • tyrosine kinase
  • advance care planning