MicroPET imaging of bacterial infection with nitroreductase-specific responsive 18 F-labelled nitrogen mustard analogues.

Lumei HuangJianyang FangShouqiang HongHuanhuan LiuHaotian ZhuLixia FengRongqiang ZhuangXilin ZhaoZhide GuoXianzhong Zhang

Published in: European journal of nuclear medicine and molecular imaging (2022)

F-NCRP are worth further investigation to verify their potential clinical application for distinguishing bacterial infection from sterile inflammation via their specific NTR responsiveness.

Keyphrases

high resolution
molecular docking
human health
drug delivery
photodynamic therapy
molecular dynamics simulations
fluorescence imaging
structure activity relationship