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Prognostic Impact of Prostate-Specific Antigen at 6 Months After Radiotherapy in Localized Prostate Cancer: An Individual Patient Data Analysis of Randomized Trials.

Lucia KwakPraful RaviJohn G ArmstrongVeronique BeckendorfJoseph L ChinAnthony V D'AmicoDavid P DearnaleySavino M Di StasiSilke Gillessen SommerHimanshu LukkaNicolas MottetPascal PommierWendy SeiferheldMatthew Robert SydesBertrand TombalAlmudena ZapateroMeredith M ReganWanling XieChristopher J Sweeney
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
PSA ≥0.1 ng/mL within 6 months after RT completion was prognostic for lt outcomes in patients treated with RT ± ADT for localized PCa. This can be used to counsel patients treated with RT ± ADT and in guiding clinical trial design evaluating novel systemic therapies with RT + ADT as well as (de)intensification strategies.
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