Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations.

Jinyong KimKyeonghun JeongHyeji JunKwangsoo KimJeong Mo BaeMyung Geun SongHanbaek YiSongyi ParkGo-Un WooDae-Won LeeTae-Yong KimKyung-Hun LeeSeock-Ah Im

Published in: Human genomics (2023)

Our study showed genetic heterogeneity of breast cancer patients with gBRCA1 and gBRCA2 mutations in the Korean populations. Further studies on precision medicine are needed for tailored treatments of patients with genetic diversity among different ethnic groups.

Keyphrases

genetic diversity
dna repair
dna damage
genome wide
breast cancer risk
copy number
smoking cessation
young adults
case control