Pan-Family Assays for Rapid Viral Screening: Reducing Delays in Public Health Responses During Pandemics.
Michael ErlichsterGursharan ChanaDaniela ZantomioBenjamin GoudeyEfstratios SkafidasPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Despite cross-reactivity with common pathogens, pan-family assays may greatly assist management of emerging pandemics through prioritization of high-resolution testing or isolation measures. Targeting highly conserved genomic regions make pan-family assays robust and resilient to mutation. A strategic stockpile of pan-family assays may improve containment of novel diseases before the availability of species-specific assays.