HeLa Cell-Derived Paclitaxel-Loaded Microparticles Efficiently Inhibit the Growth of Cervical Carcinoma.

Jinxia PengJu ZhaoYumei ZhaoPeng WuLantu GouShao Zhi FuPing ChenYun LuLinglin Yang

Published in: International journal of nanomedicine (2020)

Our results demonstrated that HeLa-derived MP-PTX significantly enhanced the anti-cancer effects of PTX with reduced toxicity, which may provide a novel strategy for the treatment of cervical carcinoma.

Keyphrases

drug delivery
cell cycle arrest
oxidative stress
combination therapy
cell proliferation