COVID-19 Patients Upregulate Toll-like Receptor 4-mediated Inflammatory Signaling That Mimics Bacterial Sepsis.

Kyung Mok Sohn Sung Gwon Lee Hyeon Ji Kim Shinhyea Cheon Hyeongseok Jeong Jooyeon Lee In Soo Kim Prashanta Silwal Young Jae Kim Seungwha Paik Chaeuk Chung Chungoo Park Yeon Sook Kim Eun-Kyeong Jo

Published in: Journal of Korean medical science (2020)

These data support a link between TLR4 signaling and pathological inflammation during COVID-19 and contribute to develop therapeutic approaches through targeting TLR4-mediated inflammation.

Keyphrases

toll like receptor
oxidative stress
inflammatory response
nuclear factor
immune response
sars cov
intensive care unit
acute kidney injury
electronic health record
big data
septic shock
drug delivery
machine learning