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Renal Denervation Prevents Atrial Arrhythmogenic Substrate Development in CKD.

Mathias HohlSimina-Ramona SelejanJan WintrichUlrike LehnertThimoteus SpeerClara SchneiderMuriel MauzPhilipp MarkwirthDickson W L WongPeter BoorAndrey KazakovMartin MollenhauerBenedikt LinzBarbara Mara KlinkhammerUlrich HübnerChristian UkenaJulia MoellmannMichael LehrkeStefan WagenpfeilChristian WernerDominik K LinzFelix MahfoudMichael Böhm
Published in: Circulation research (2022)
In an experimental rat model of CKD, RDN inhibited progression of atrial structural and electrophysiological remodeling. Therefore, RDN represents a potential therapeutic tool to reduce the risk of AF in CKD, independent of changes in renal function and blood pressure.
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