Individual risk prediction of high grade prostate cancer based on the combination between total prostate-specific antigen (PSA) and free to total PSA ratio.
Simona FerraroDavide BiganzoliRoberta Simona RossiFranco PalmisanoMarco BussettiEnrica VerzottiAndrea GregoriFilippo BianchiMarco MaggioniFerruccio CeriottiCristina CeredaGianvincenzo ZuccottiPeter KavsakMaria Rosaria CapobianchiGiuseppe MaranoElia Mario BiganzoliPublished in: Clinical chemistry and laboratory medicine (2023)
The estimated risk of high or low grade PCa by the nomograms may be of aid in the decision-making process, in particular in the case of critical comorbidities and when the digital rectal examinations are inconclusive. The improved characterization of the risk of ISUP≥3 might enhance the use for magnetic resonance imaging in this setting.