The association of T786C and G894T polymorphisms of eNOS gene with diabetic retinopathy in Greece.

Nikolaos S GouliopoulosGerasimos SiasosDimitra OikonomouEvangelos OikonomouTheodosia KonsolaChristina KolliaDimitris AthanasiouStathis DimitropoulosAlexandros RouvasEva KassiDimitrios TousoulisMarilita M Moschos

Published in: European journal of ophthalmology (2021)

We documented that rs1799983 GT genotype could be recognized as an independent risk factor of retinopathy in Greek patients with type-2 diabetes mellitus, while no role for rs2070744 polymorphism was identified. Further research in different ethnic groups will clarify the exact association of these polymorphisms with the risk for diabetic retinopathy development.

Keyphrases

diabetic retinopathy
optical coherence tomography
end stage renal disease
ejection fraction
risk factors
newly diagnosed
chronic kidney disease
endothelial cells
nitric oxide
patient reported outcomes
cell proliferation
pi k akt
molecular dynamics
nitric oxide synthase