Asleep Surgery May Improve the Therapeutic Window for Deep Brain Stimulation of the Subthalamic Nucleus.
Farhad SenemmarChristian J HartmannPhilipp J SlottyJan VesperAlfons SchnitzlerStefan Jun GroissPublished in: Neuromodulation : journal of the International Neuromodulation Society (2020)
Our study provides first evidence for improvement of therapeutic window by asleep surgery compared to awake surgery, which can be strengthened further by dDBS. These results support the notion of preferring asleep over awake surgery but needs to be confirmed by prospective trials.