Rare Orbital Involvement Originating from Extranodal Marginal Zone Lymphoma.
Yao-Chang WenTzu-Chuan HuangWen-Chiuan TsaiShiue-Wei LaiPublished in: Medicina (Kaunas, Lithuania) (2024)
Ocular adnexa region (OAR) primary lymphomas are uncommon, accounting for 1-2% of non-Hodgkin lymphomas and 8% of extranodal lymphomas. Extranodal marginal zone lymphoma (EMZL) originates from several epithelial tissues, including the stomach, salivary gland, lung, small intestine, thyroid gland, and ocular adnexa region. Here, we report a 66-year-old female patient who was diagnosed with EMZL of OAR. In consideration of the possible side effect of radiotherapy, such as conjunctivitis, visual acuity impairment, and even retinal complications, she received six cycles of triweekly targeted chemotherapy with rituximab, cyclophosphamide, vincristine, and prednisone (R-CVP) without radiotherapy. Then, she remained in complete remission up to the present day.
Keyphrases
- diffuse large b cell lymphoma
- locally advanced
- early stage
- optic nerve
- radiation therapy
- hodgkin lymphoma
- rectal cancer
- radiation induced
- optical coherence tomography
- squamous cell carcinoma
- gene expression
- case report
- low dose
- high dose
- diabetic retinopathy
- cancer therapy
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus