Identification of gastrointestinal perforation based on ICD-10 code in a Japanese administrative medical information database and associated drug exposure risk factors.
Masatoshi TanigawaYoko KataokaTakayoshi KishinoMei KohamaYoshiaki UyamaYasuyuki SuzukiHideto YokoiPublished in: Pharmacoepidemiology and drug safety (2019)
Although the overall PPV for GI perforation based on ICD-10 code was low, our results suggest that the PPV could be improved by appropriate selection of DPC diagnosis category and that use of multiple medications enhances the risk of GI perforation.