Long-term follow-up of treatment-naïve HBeAg-negative patients with chronic hepatitis B.
Yusuf Emre OzdemirMeryem Sahin OzdemirOsman Faruk BayramlarSerkan SürmeSibel Yıldız KayaRidvan KaraaliI Lker İnanç BalkanBilgül MeteNeşe SaltoğluÖmer Fehmi TabakPublished in: Irish journal of medical science (2022)
CVR was achieved at similar rates with all four antiviral agents, while younger age (≤ 40) and low baseline viral load were the main factors for virological response. However, drug resistance and virological breakthrough in the LAM group and side effects in the LdT group were detected during the long-term follow-up. Moreover, HBsAg seroclearance was achieved at very low rates with oral antiviral agents.