Exploring Safety in Gender-Affirming Hormonal Treatments: An Observational Study on Adverse Drug Events Using the Food and Drug Administration Adverse Event Reporting System Database.
Ainhoa Gómez-LumbrerasLorenzo Villa-ZapataPublished in: The Annals of pharmacotherapy (2024)
The FAERS data reveal significant ADRs in transgender individuals using hormone therapy, sometimes unintended for their recipient gender. Population-level studies are crucial to enhance transgender health care. Spontaneous surveillance databases like FAERS illuminate off-label ADRs, urging health care providers to approach hormone therapies with informed caution.
Keyphrases
- adverse drug
- drug administration
- healthcare
- electronic health record
- hiv testing
- emergency department
- mental health
- big data
- public health
- drug induced
- genome wide
- polycystic ovary syndrome
- men who have sex with men
- stem cells
- metabolic syndrome
- machine learning
- case control
- dna methylation
- bone marrow
- climate change
- mesenchymal stem cells
- adipose tissue
- smoking cessation
- antiretroviral therapy