Transcriptome Changes and Metabolic Outcomes After Bariatric Surgery in Adults With Obesity and Type 2 Diabetes.
Mamoon RashidAli Al QarniSaeed Al MahriSameer MohammadAltaf KhanMashan L AbdullahCynthia LeheReem Al AmoudiOmar S AldibasiAbderrezak BouchamaPublished in: Journal of the Endocrine Society (2023)
The changes in the transcriptome after bariatric surgery distinguish patients in whom diabetes enters complete remission from those who do not. The baseline transcriptome can contribute to the prediction of bariatric surgery-induced diabetes remission preoperatively.
Keyphrases
- type diabetes
- glycemic control
- bariatric surgery
- rna seq
- weight loss
- cardiovascular disease
- single cell
- genome wide
- gene expression
- end stage renal disease
- insulin resistance
- ejection fraction
- chronic kidney disease
- newly diagnosed
- metabolic syndrome
- disease activity
- prognostic factors
- dna methylation
- systemic lupus erythematosus
- obese patients
- oxidative stress
- physical activity
- adipose tissue
- patient reported outcomes
- weight gain