PFAS Levels, Early Life Factors, and Mammographic Breast Density in Premenopausal Women.

Yitao S NingKayla R GetzJoy K KyeyuneMyung Sik JeonChongliang LuoJingqin LuoAdetunji T Toriola

Published in: Environmental health perspectives (2024)

We report novel associations of PFHxS and PFOS with DV in premenopausal women. PFOS, PFOA, and PFHxS were not associated with VPD and NDV. In addition, body shape at age 10 may modify the associations of PFOS with MBD. Further studies are needed to validate our findings and to evaluate the associations of other per- and polyfluoroalkyl substances (PFAS), as well as mixtures of PFAS, with MBD. https://doi.org/10.1289/EHP14065.

Keyphrases

breast cancer risk
early life
polycystic ovary syndrome
postmenopausal women
pregnancy outcomes
cervical cancer screening
drinking water
adipose tissue
early breast cancer