Nickel-Catalyzed Intramolecular Direct Arylation of Imines toward Diverse Indoles.
Han LongKunhua XuShanshan ChenJin LinDan WuBo WuXu TianHarry L AndersonPublished in: Organic letters (2019)
An efficient nickel-catalyzed intramolecular direct arylation of imines with challenging aryl chlorides has been developed. The versatile nickel catalysis made use of easily accessible imines and delivered diversely decorated 2-arylindoles of considerable importance to biological and medicinal chemistry.