Signatures of exposure to childhood trauma in young adults in the structure and neurochemistry of the superior temporal gyrus.
Piril HepsomaliSandra MachonHolly BarkerDavid J LythgoeKenneth HugdahlMaria GudbrandsenPaul AllenPublished in: Journal of psychopharmacology (Oxford, England) (2023)
This study provides the first evidence that both low GABA concentrations and its interaction with GMV in the left STG are associated with high levels of CT and suggest that altered inhibitory neurotransmission/metabolism may be linked to a lower GMV in the left STG in adults who experienced CT. Future studies are warranted to establish if utilizing these measures can stratify clinical high-risk and predict future clinical outcomes in high CT individuals.