In1-Ghrelin Splicing Variant as a Key Element in the Pathophysiological Association Between Obesity and Prostate Cancer.

Juan M Jiménez-VacasAntonio J Montero-HidalgoEnrique Gómez-GómezAntonio C Fuentes-FayosFrancisco Ruiz-PinoIpek GulerAntonio CamargoFrancisco J AngladaJulia Carrasco-ValienteManuel Tena-SempereAndré Sarmento-CabralJusto P CastañoManuel D Gahete Raul Miguel Luque

Published in: The Journal of clinical endocrinology and metabolism (2021)

Urine In1-ghrelin levels are associated with obesity-related factors and PCa risk and aggressiveness and could represent a novel and valuable noninvasive PCa biomarker, as well as a potential link in the pathophysiological relationship between obesity and PCa.

Keyphrases

insulin resistance
metabolic syndrome
prostate cancer
weight loss
high fat diet induced
type diabetes
weight gain
radical prostatectomy
adipose tissue
skeletal muscle
growth hormone