Whispers in the wind: Face mask sampling for Mycobacterium tuberculosis detection in children with pulmonary tuberculosis.
Lennard MeiwesIrina KontsevayaDumitru ChesovStela KulciţkaiaViola DreyerDoris HillemannQiniso DlaminiCaroline WilliamsMichael BarerFolke BrinkmannRenate KrügerStephanie TheeAlexander W KayAnna Maria MandalakasChristoph LangePublished in: The Journal of infectious diseases (2024)
Paediatric FMS has a low limit of detection for M. tuberculosis-specific DNA in vitro. However, M. tuberculosis DNA was not detected in any of thirty masks worn by children with pulmonary TB. This suggests that FMS in this form may not be more effective for detecting M. tuberculosis in children with TB than existing methods.
Keyphrases
- mycobacterium tuberculosis
- pulmonary tuberculosis
- tyrosine kinase
- young adults
- circulating tumor
- emergency department
- single molecule
- intensive care unit
- cell free
- loop mediated isothermal amplification
- real time pcr
- label free
- obstructive sleep apnea
- nucleic acid
- adverse drug
- positive airway pressure
- sensitive detection