Heart Rate Dependence of the Pulmonary Resistance x Compliance (RC) Time and Impact on Right Ventricular Load.
Thomas S MetkusChristopher J MullinE Wilson GrandinJ Eduardo RameEmmanouil TampakakisSteven HsuTodd M KolbRachel DamicoPaul M HassounDavid A KassStephen C MathaiRyan J TedfordPublished in: PloS one (2016)
Heart rate and BSA are associated with pulmonary RC time. As heart rate increases, the pulsatile and total load on the RV also increase. This relationship supports a hemodynamic mechanism for adverse effects of tachycardia on the RV.