LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis.

Yun-Ping HuYun-Peng JinXiang-Song WuYang YangYong-Sheng LiHuai-Feng LiShan-Shan XiangXiao-Ling SongLin JiangYi-Jian ZhangWen HuangShi-Li ChenFa-Tao LiuChen ChenQin ZhuHong-Zhuan ChenRong ShaoYing-Bin Liu

Published in: Molecular cancer (2019)

Our study demonstrates that lncRNA-HGBC promotes GBC metastasis via activation of the miR-502-3p-SET-AKT cascade, pointing to lncRNA-HGBC as a new prognostic predictor and a therapeutic target.

Keyphrases

long non coding rna
signaling pathway
cell proliferation
long noncoding rna
papillary thyroid
squamous cell
binding protein
young adults
lymph node metastasis
childhood cancer