Articular cartilage degeneration and bone adaptation due to lack of dystrophin in mice.
José Fontes Dos SantosMariana Cruz LazzarinVivianne Izabelle de Araújo BaptistaHananiah Tardivo QuintanaDaniel Araki RibeiroFlavia de OliveiraPublished in: Journal of bone and mineral metabolism (2021)
The morphological changes observed in the bone tissue of the MDX may be not only secondary to muscle weakness or chronic use of corticosteroids but also our results indicate connections between decrease of cartilage thickness, collagen network alteration and consequent subchondral changes that may lead to articular cartilage degeneration and bone adaptation mechanism in MDX mice.