Muscle Mitochondrial Bioenergetic Capacities Are Associated With Multimorbidity Burden in Older Adults: The Study of Muscle, Mobility and Aging.
Theresa MauTerri L BlackwellPeggy M CawthonAnthony J A MolinaPaul M CoenGiovanna DistefanoPhilip A KramerSofhia V RamosDaniel E FormanBennett P GreenwoodFrederico G S ToledoKate A DuchownyLauren M SparksAnne B NewmanStephen B KritchevskySteven R CummingsPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)
Lower muscle mitochondrial bioenergetic capacities were associated with a worse composite multimorbidity index score. Our results suggest that decrements in muscle mitochondrial energetics may contribute to a greater global burden of disease and are more strongly related to some conditions than others.