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Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis.

Diyan ChenGaogan JiaYanping ZhangHuanyu MaoLiping ZhaoWenyan LiYan ChenYusu Ni
Published in: Journal of neuroinflammation (2022)
These results demonstrate a novel protective role of Sox2 in mature and terminally differentiated cochlear hair cells by inhibiting inflammation.
Keyphrases
  • hearing loss
  • oxidative stress
  • transcription factor
  • induced apoptosis
  • signaling pathway
  • diabetic rats
  • cell proliferation
  • stem cells
  • cell cycle arrest
  • high glucose
  • drug induced
  • air pollution
  • mouse model
  • pi k akt