Two-day versus seven-day course of levofloxacin in acute COPD exacerbation: a randomized controlled trial.

Salma MessousImen TrabelsiBel Haj Ali KhaoulaAhmed AbdelghaniYosra Ben DayaRabie RazgallahMohamed Habib GrissaKaouthar BeltaiefZied MezgarAsma BelguithWahid BouidaRiadh BoukefHamdi BoubakerMohamed Amine MsolliAdel SekmaSemir Nouira

Published in: Therapeutic advances in respiratory disease (2022)

Levofloxacin once daily for 2 days is not inferior to 7 days with respect to cure rate, need for additional antibiotics and hospital readmission in AECOPD. Our findings would improve patient compliance and reduce the incidence of bacterial resistance and adverse effects.

Keyphrases

chronic obstructive pulmonary disease
respiratory failure
liver failure
lung function
case report
risk factors
healthcare
physical activity
drug induced
aortic dissection
acute care
adverse drug
extracorporeal membrane oxygenation
emergency department
hepatitis b virus
acute respiratory distress syndrome