Mutation profile of high-grade appendiceal mucinous neoplasm.
Xiaoyan LiaoVera VavinskayaKatherine SunYansheng HaoXiaodong LiMark ValasekRuliang XuAlexandros D PolydoridesJane HouldsworthNoam HarpazPublished in: Histopathology (2019)
HAMN and LAMN share high rates of KRAS and GNAS co-mutations supporting a common histogenesis and distinguishing them from MACA. Acquisition of TP53 or ATM mutations by HAMN may drive its progression to a more advanced phenotype.