Optimal Timing for Resumption of Anticoagulation After Intracranial Hemorrhage in Patients With Mechanical Heart Valves.
Megan E BarraRachel FormanBianca Long-FazioAlexander E MerklerMahmut Edip GurolSaef IzzyRicha SharmaPublished in: Journal of the American Heart Association (2024)
In this study of patients with ICH and mechanical heart valves, there was no difference in 30-day thrombotic and hemorrhagic brain-related outcomes when anticoagulation was resumed within 7 versus 7 to 30 days after ICH. Withholding anticoagulation >30 days was associated with severe baseline ICH, higher in-hospital case fatality, and elevated AIS risk.
Keyphrases
- atrial fibrillation
- venous thromboembolism
- aortic valve
- heart failure
- aortic valve replacement
- healthcare
- white matter
- early onset
- type diabetes
- drug induced
- emergency department
- adipose tissue
- acute care
- blood brain barrier
- cerebral ischemia
- multiple sclerosis
- transcatheter aortic valve implantation
- optical coherence tomography
- left ventricular
- brain injury
- electronic health record
- aortic stenosis
- ejection fraction