MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth.

Olivia J ChengEric J LebishOwen JensenDamian JacenikShubhanshi TrivediJackson CacioppoJeffrey AubéEllen J BeswickDaniel T Leung

Published in: bioRxiv : the preprint server for biology (2024)

In models of colon cancer, MAIT cells have anti-tumor activity, associated with increased production of proinflammatory and eosinophil-modulating cytokines.

Keyphrases

induced apoptosis
cell cycle arrest
immune response
signaling pathway
endoplasmic reticulum stress
cell proliferation
pi k akt