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Machine-learning derived heart and brain age are independently associated with cognition.

Olena IakunchykovaHenrik SchirmerTorgil VangbergYunpeng WangErnest Diez BenaventeRené van EsRutger R van de LeurHaakon LindekleivZachi I AttiaFrancisco Lopez-JimenezDavid A LeonTom Wilsgaard
Published in: European journal of neurology (2023)
HDA, representing cumulative effects of life-long exposures, was associated with brain age. HDA was associated with cognitive function that was minimally explained through BDA.
Keyphrases
  • white matter
  • machine learning
  • resting state
  • histone deacetylase
  • heart failure
  • artificial intelligence
  • atrial fibrillation
  • multiple sclerosis
  • big data
  • deep learning
  • brain injury