Rho-Kinase Inhibition Improves the Outcome of Focal Subcortical White Matter Lesions.

Sanem A Aykan Hongyu XieYi ZhengDavid Y ChungSreekanth KuraJames Han LaiTaylan D ErdoganAndréia Albuquerque Cunha Lopes-de-Morais Isra Tamim Damla Yagmur Hidehiro IshikawaKen AraiM Abbas YaseenDavid A Boas Sava SakadzicCenk Ayata

Published in: Stroke (2022)

These data show that delayed fasudil posttreatment improves functional outcomes after a focal subcortical white matter lesion in mice. Future work will aim to elucidate the mechanisms.

Keyphrases

white matter
multiple sclerosis
protein kinase
electronic health record
current status
high fat diet induced
big data
tyrosine kinase
type diabetes
machine learning
skeletal muscle