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Tumor Microenvironment Modulates Invadopodia Activity of Non-Selected and Acid-Selected Pancreatic Cancer Cells and Its Sensitivity to Gemcitabine and C18-Gemcitabine.

Tiago Miguel Amaral CarvalhoMadelaine Magalì AuderoMaria Raffaella GrecoMarilena ArdoneTeresa MaggiRosanna MallamaciBarbara RolandoSilvia ArpiccoFederico Alessandro RuffinattiAlessandra Fiorio PlaNatalia PrevarskayaTomas KoltaiStephan Joel ReshkinRosa Angela Cardone
Published in: Cells (2024)
We propose C18 as a more effective approach to conventional GEM in developing new therapeutic strategies overcoming PDAC chemoresistance.
Keyphrases
  • locally advanced
  • rectal cancer