Stroke in Pregnancy and Preeclampsia: Effect of Low-Dose Aspirin Treatment on Collateral Flow Velocity and Cerebral Blood Flow Autoregulation During Ischemia in Rats.
Marilyn J CipollaSarah M TremblePublished in: Journal of the American Heart Association (2024)
Low-dose aspirin in ePE reduced infarction that was associated with increased vasodilator prostacyclin and improved collateral perfusion during induced hypertension. The beneficial effect of aspirin on the brain and cerebral circulation is likely multifactorial and worth further study.
Keyphrases
- low dose
- cerebral blood flow
- high dose
- blood pressure
- cerebral ischemia
- atrial fibrillation
- pregnancy outcomes
- high glucose
- early onset
- subarachnoid hemorrhage
- pulmonary arterial hypertension
- white matter
- resting state
- diabetic rats
- preterm birth
- magnetic resonance
- functional connectivity
- type diabetes
- endothelial cells
- magnetic resonance imaging
- multiple sclerosis
- antiplatelet therapy
- combination therapy
- oxidative stress
- replacement therapy