Mesothelial/monocytic incidental cardiac excrescence in autoimmune disease.
Vera CeteraNunzio Davide de MannaIlaria GirolamiEnrico CavalloAlbino EccherAlessio RungatscherGiovanni Battista LucianiAldo D MilanoGiuseppe FaggianPublished in: Journal of cardiac surgery (2019)
Mesothelial/monocytic incidental cardiac excrescence (MICE) is a rare benign finding made of mesothelial cells, histiocytes, and fibrin, usually found during heart valve surgery. The clinical relevance resides in the potential misdiagnosis as metastatic carcinoma or arterial embolism. The pathogenesis remains uncertain, with artifactual and reactive hypotheses. Here we present a case of MICE with paradigmatic clinical, imaging, and histological features in a 28-year-old woman with undifferentiated connective tissue disease without previous cardiac catheterization with possible pathogenesis, highlighting the importance of awareness of the existence of this lesion in patients with autoimmune disease.
Keyphrases
- left ventricular
- multiple sclerosis
- squamous cell carcinoma
- minimally invasive
- small cell lung cancer
- mitral valve
- high fat diet induced
- high resolution
- type diabetes
- high glucose
- oxidative stress
- coronary artery bypass
- atrial fibrillation
- coronary artery disease
- mass spectrometry
- signaling pathway
- insulin resistance
- aortic stenosis
- wild type
- endoplasmic reticulum stress