Structural and functional annotation of solute carrier transporters: implication for drug discovery.
Vojtech DvorakGiulio Superti-FurgaPublished in: Expert opinion on drug discovery (2023)
Recent progress in the structural and functional annotations allows to refine the SLC druggability index. Particularly the increasing number of experimentally solved structures of SLCs provides insights into mode-of-action of a significant number of chemical modulators of SLCs.