Female sex as a risk factor for ischaemic stroke varies with age in patients with atrial fibrillation.

Victor Chien-Chia WuMichael WuVictor AboyansShang-Hung ChangShao-Wei ChenMien-Cheng ChenChun-Li WangI-Chang HsiehPao-Hsien Chu Yung-Lung Chen

Published in: Heart (British Cardiac Society) (2019)

The female/male ischaemic stroke risk ratio varied with age. Only women aged >75 years had a higher risk, whereas women aged <65 years had a lower risk compared with men. These findings challenge the 'sex category' component of the CHA2DS2-VASc score, used to make decision regarding anticoagulation treatment in AF patients.

Keyphrases

atrial fibrillation
polycystic ovary syndrome
end stage renal disease
ejection fraction
chronic kidney disease
breast cancer risk
prognostic factors
pregnancy outcomes
adipose tissue