Synaptic and brain-expressed gene sets relate to the shared genetic risk across five psychiatric disorders.

Anke R Hammerschlag Christiaan A de Leeuw Christel M Middeldorp Tinca J C Polderman

Published in: Psychological medicine (2019)

We obtained novel evidence for shared biological mechanisms that act across psychiatric disorders and we showed that several gene sets that have been related to individual disorders play a role in a broader range of psychiatric disorders.

Keyphrases

genome wide
copy number
genome wide identification
resting state
white matter
gene expression
multiple sclerosis
functional connectivity
transcription factor
genome wide analysis
subarachnoid hemorrhage