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Synaptic and brain-expressed gene sets relate to the shared genetic risk across five psychiatric disorders.

Anke R HammerschlagChristiaan A de LeeuwChristel M MiddeldorpTinca J C Polderman
Published in: Psychological medicine (2019)
We obtained novel evidence for shared biological mechanisms that act across psychiatric disorders and we showed that several gene sets that have been related to individual disorders play a role in a broader range of psychiatric disorders.
Keyphrases
  • genome wide
  • copy number
  • genome wide identification
  • resting state
  • white matter
  • gene expression
  • multiple sclerosis
  • functional connectivity
  • transcription factor
  • genome wide analysis
  • subarachnoid hemorrhage