Genetic heterogeneity and enrichment of variants in DNA-repair genes in ameloblastoma.
Waheed AwotoyeJoseph Craig WhittByunggil YooMidhat S FarooqiEmily G FarrowVeerasathpurush AllareddyBrad A AmendtShankar Rengasamy VenugopalanPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2023)
The variants identified in follicular and plexiform ameloblastomas were enriched in DNA-repair genes. The observed genetic heterogeneity in these ameloblastomas may contribute to the aggressive nature and recurrence risk of these tumors.