Cytotoxic Effects of Common Irrigation Solutions on Chondrosarcoma and Giant Cell Tumors of Bone.
Chris MooreRussell J FernandesJorge Manrique-SuccarNayak L PolissarLjubomir MiljacicDaniel S HippeJonathon VauxMatthew J ThompsonPublished in: The Journal of bone and joint surgery. American volume (2022)
In an effort to reduce the burden of residual tumor cells, irrigation solutions are often utilized as adjuvant local therapy. Use of a 0.05% CHG solution clinically could serve as a potential chemical adjuvant to intralesional curettage of chondrosarcoma and GCT. Further in vivo studies may be indicated to assess clinical outcomes and safety associated with the use of 0.05% CHG in the treatment of chondrosarcoma and GCT.