Clinical significance of interstitial lung abnormalities and immune checkpoint inhibitor-induced interstitial lung disease in patients with non-small cell lung cancer.

Daiki Murata Koichi AzumaGoushi MatamaYoshiaki ZaizenNorikazu MatsuoKenta MurotaniTakaaki TokitoTomoaki Hoshino

Published in: Thoracic cancer (2022)

The presence of nonfibrotic ILAs is a significant risk for early-onset ICI-ILD in patients with NSCLC undergoing ICI monotherapy. Clinicians should be aware of ILAs, especially nonfibrotic ILAs, before administering ICIs to lung cancer patients.

Keyphrases

interstitial lung disease
early onset
systemic sclerosis
rheumatoid arthritis
late onset
idiopathic pulmonary fibrosis
small cell lung cancer
high glucose
diabetic rats
palliative care
advanced non small cell lung cancer
oxidative stress
epidermal growth factor receptor