IgG from atopic dermatitis patients induces IL-17 and IL-10 production in infant intrathymic TCD4 and TCD8 cells.

Fábio D R SgnottoMarilia G de OliveiraAline A L LiraAmanda H S InoueTiago O TitzRaquel L OrfaliLuciana Bento-de-SouzaMaria N SatoValeria AokiAlberto J S DuarteJefferson Russo Victor

Published in: International journal of dermatology (2018)

IgG of AD patients can stimulate cytokine production in infant thymocytes and thus resembles the peripheral profile observed in adults. These findings suggest a novel mechanism that can contribute to AD pathogenesis.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
atopic dermatitis
induced apoptosis
patient reported outcomes
cell death
oxidative stress
signaling pathway
pi k akt