Autonomic dysfunction in hereditary spastic paraplegia type 4.

Carelis González-SalazarK A G TakazakiAlberto Rolim Muro MartinezL R Pimentel-SilvaL A Jacinto-ScudeiroÉ Y NakagawaC E Fujiwara MurakamiJ A M SauteJ L PedrosoO G P BarsottiniH A G TeiveM C França

Published in: European journal of neurology (2019)

Our results indicate that SPG4-HSP patients have sudomotor dysfunction caused by damaged small post-ganglionic cholinergic fibers. Damage in SPG4-HSP extends to the peripheral nervous system.

Keyphrases

oxidative stress
heat shock protein
end stage renal disease
newly diagnosed
heat stress
prognostic factors
peritoneal dialysis
heart rate variability
heart rate
blood pressure
patient reported
upper limb