Genomic investigation of bone tuberculosis highlighted the role of subclinical pulmonary tuberculosis in transmission.
Jinfeng YinGuangxuan YanLiyi QinChendi ZhuJun FanYuwei LiJunnan JiaZhaojun WuHui JiangMuhammad Tahir KhanJiangdong WuNaihui ChuHoward E TakiffQian GaoShibing QinQingyun LiuWeimin LiPublished in: Tuberculosis (Edinburgh, Scotland) (2024)
This study provides genomic evidence that bone TB patients without clinically diagnosed PTB can be sources of TB transmission, underscoring the importance of screening for subclinical, transmissible PTB among EPTB cases.
Keyphrases
- pulmonary tuberculosis
- mycobacterium tuberculosis
- end stage renal disease
- bone mineral density
- ejection fraction
- newly diagnosed
- copy number
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- emergency department
- soft tissue
- drinking water
- postmenopausal women
- bone loss
- gene expression
- body composition
- dna methylation
- patient reported