Nitrogen Permease Regulator-Like-2 Exhibited Anti-Tumor Effects And Enhanced The Sensitivity Of Colorectal Cancer Cells To Oxaliplatin And 5-Fluorouracil.

Aiyun LiuJiutao QiaoLiyuan HeZhangmeng LiuJing ChenFenghua PeiYaju Du

Published in: OncoTargets and therapy (2019)

Our present work demonstrated that NPRL2 exhibited anti-tumor effects and enhanced the sensitivities of CRC cells to L-OHP and 5-FU through the P-gp and MRP1 pathways.

Keyphrases

oxidative stress
cell death
signaling pathway