Breast milk IgA to foods has different epitope specificity than serum IgA-Evidence for entero-mammary link for food-specific IgA?
Antti E SeppoE M SavilahtiM C BerinH A SampsonKirsi M JärvinenPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
These findings support the concept that mother's milk has a distinct antifood antibody repertoire when compared to the antibody repertoire of the peripheral blood. Increased binding of serum epitope-specific IgA to CM in mothers of infants with CMA may reflect inherited systemic immunogenicity of CM proteins in these families, although specific IgA in breast milk was not proportionally up-regulated.