Asthma-related inflammation promotes lung metastasis of breast cancer cells through CCL11-CCR3 pathway.
S BekaertN RocksC VanwingeA NoelDidier CataldoPublished in: Respiratory research (2021)
Allergic inflammation generated by exposure to allergens triggers the implantation of metastatic cells from primary breast tumor into lung tissues plausibly in a CCL11-CCR3-dependent manner. This indicates that asthma related inflammation in lungs might be a risk factor for lung metastasis in breast cancer patients.