Levodopa-carbidopa intestinal gel for advanced Parkinson's disease: Impact of LRRK2 and GBA1 mutations.

Avner ThalerSaar AnisPenina PongerTsviya Fay-KarmonVered LivnehAchinoam Faust-SocherLior GreenbaumJohnathan ReinerAriela HilelHertzel ShabtaiRoy N AlcalayRuth DjaldettiSharon Hassin-BaerAdi EzraAnat MirelmanNir GiladiTanya Gurevich

Published in: Parkinsonism & related disorders (2024)

Overall, LCIG treatment was well tolerated in LRRK2-PD and GBA1-PD. GBA1-PD required LCIG earlier in their course of their disease and had higher frequencies of hallucinations during treatment, attesting to a more severe disease course.

Keyphrases

parkinson disease
early onset