Study of the Possible Alleviated Role of Atorvastatin on Irinotecan-Induced Lingual Mucosal Damage: Histological and Molecular Study.

Eetmad A ArafatS M Abo El-KhairA Z ElsamanoudyDalia A Shabaan

Published in: Oxidative medicine and cellular longevity (2021)

Atorvastatin substantially attenuates CPT-11-induced oral mucositis through the initiation of the antiapoptotic gene, modulation of the inflammatory, and antioxidant gene expression.

Keyphrases

gene expression
oxidative stress
diabetic rats
high glucose
dna methylation
radiation induced
drug induced
copy number
genome wide
endothelial cells